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I've been on Pristiq now for about 4 months. I could tell the difference in my moods almost right away. Every little thing used to make me cry, but not any longer. The only side effect I experienced was dry mouth. Really wish I could have felt a decrease in appetite. The withdrawals are pretty bad for me though. One day I forgot to take it and almost pulled my hair out. I was crying uncontrollably over nothing which I didn't even do before taking the medicines. I was also having major brain zaps. I recommend coming off slowly. All in all though, I love it.

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This drug has been a miracle for me. I take it with Abilify (5 mgs) - and it has been a God-send. I was on a triple combination of Cymbalta, Welbutrin and Abilify and still did not feel well. Pristiq has helped me tremendously from within a week of onset. I have struggled with depression since 1991 - and have been on a variety of "cocktails" but this one is working the best so far. I still struggle with sleep and anxiety - as I have problems with Doctors treating my anxiety disorder as it should be. Interesting that physicians will treat some things an not others. My only complaint is lacking in sleep - other wise I would recommend this medicine to anyone struggling with depression.

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